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Case Report: Arginine Chloride Extravasation-Induced Skin Necrosis in Infant

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A 10-month-old female with medical history of respiratory failure, acute hypoxic renal injury and sepsis secondary to intubation-dependent chronic lung disease of prematurity was started on arginine chloride via peripheral intravenous line, 5 grams every 8hours (25mEq per dose), for management of metabolic alkalosis and hypochloremia of renal insufficiency. Twelve hours after the start of infusion, nursing staff noticed blistering at the IV site during a routine skin exam.

Authors:   Katherine Reuter Mu​ñoz; Adam Goodreau, MD; Daniel Luppens, MD

Subspecialty: Reconstructive/Microsurgery

Disclaimer: The content and CPT codes included in this case report are accurate up to and on the publication date. Please note that CPT codes may change; and the ones included are specific to this case  at the time of publication.  It is recommended that you check with the appropriate coding resources for the most current codes and application.

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Product Code: 31112